The Common Alkaloids in the Kratom Plant

The mitragyna speciosa is a 4-16 meter tall tropical tree native to South East Asia, New Guinea and the Philippines. However, now it is being cultivated in other parts of the world. People in Thailand call the tree and all of its leaf preparations by the name of Kratom. Conventionally, people chew dried or fresh Kratom leaves, and sometimes they are used in tea. It is not very common to use them for smoking.

The low dose of Kratom leaves has stimulating effects, used to fight against fatigue when you feel low-powered during extended work hours. A person may experience calming narcotic effects after taking a slightly high dosage. Pure Kratom can be obtained from the Golden Monk, where you can see this available in different forms.

Kratom is also utilized in different types of medicines as a substitute for opium. The phytochemicals separated from different portions of the tree contain more than forty architecturally related alkaloids as well as many polyphenols, flavonoids, terpenoid saponins, and glycosides. However, the key psychoactive components in the leaves of this tree are 7-hydroxymitragynine and mitragynine.

Here are the common Alkaloids that are found in the Kratom plant.


The indole alkaline. Mitragynine is the basic alkaloid found in kratom, and considered to be responsible for most of the effects of this particular herb. This is approximately 66% of the total alkaloid content found in kratom leaves.


This can be the smooth muscle relaxer, but nothing can be confirmed as of now due to limited availability of research work. This is around 8.6% to 9% of the entire alkaloid content found in kratom leaf. Paynantheine is the second richest alkaloid.


This is considered to be the muscle relaxer as well. About 6.6% to 7% of the total alkaloid contents in kratom leaf, demonstrating the third most plentiful alkaloid.


The 7-hydroxymitragynine along with mitragynine is liable for the basic effects of Kratom. It shows approximately 2% of the complete alkaloid content seen in Kratom leaves. This is variable because some of the leaves have undetectable levels.


This could be the possible muscle relaxer for people looking to relax their muscles. This is less than 1% of the entire alkaloid contents in Kratom leaves.


It is also less than 1% of the complete alkaloid content seen in Kratom leaves.


The indole alkaloid is also seen in the claw of Chinese Cat (Uncaria tomentosa). This is less than 1% of all the alkaloid contents of Kratom leaves. It can be useful in improving the feelings of happiness.


It seems to have effects on the 5-HT and dopamine receptors. Uncaria tomentosa (Claw of Chinese Cat) has been seen to include rhynchophylline. This has a related chemical construction to mitragynine. The Rhynchophylline represents less than 1% of the complete alkaloid content from Kratom leaves.


Structurally it is related to yohimbe alkaloids. It is likely to have hypertensive effects on people. It may also cause a reduction of serotonin and catecholamine stores in different body organs. Studies have shown the existence of ajmalicine in Rauwolfia serpentine.

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